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As with most addictive substances, nicotine activates the brains reward circuits and also increases levels of a chemical messenger in the brain called dopamine , which reinforces rewarding behaviors

The tobacco industry's image took a beating in the 1990s, with the leak of industry documents showing that cigarette companies had hidden evidence that nicotine was addictive, Glantz says

Sbastien Buemi, Brendon Hartley and Ry Hirakawa are also in the title fight, just 19 points adrift of their team-mates, after finishing third at Le Mans in the No8 TR010 Hybrid

How It Works: Quitines 2mg lozenges slowly dissolve in your mouth, releasing nicotine that is absorbed through the lining of your cheek

Weight: ~45 g