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Cui et al., 2019)

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Beneficial commensals generally promote immune tolerance and help reinforce the intestinal barrier, whereas an overgrowth of pathogenic bacteria or loss of key symbionts (dysbiosis) can provoke systemic inflammation [34]

J Hum Nutr Diet

8-10 weeks old EGFR flox/flox mice were injected adeno associated virus 8 (AAV-8) expressing Cre recombinase with a thyroxin binding globulin (TBG) promoter (hepatocyte-specific promoter) to knockout EGFR in hepatocytes (EGFR KO)