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In addition to the findings with ASMase knockout mice, which models the lysosomal storage disorder NiemannPick type A disease, inhibition of glucocerebrosidase in hepatocytes by conduritol -epoxide, a cellular model of Gaucher disease that exhibits lysosomal cholesterol accumulation sensitizes to APAP-induced cell death (Teratani et al., 2017)

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Australia's regulatory alignment with FDA/EMA decisions means local approval timelines would likely lag global approval by 1224 months

Esta doble accin, que mejora tanto la migracin como la proliferacin celular, acelera el proceso de cierre de la herida y favorece la formacin de tejido nuevo y sano

MV: Investigation, Methodology, Writingoriginal draft