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When excessive ROS production exceeds the effective capacity of cellular antioxidants, oxidative stress occurs, disrupting redox homeostasis and impairing cellular components such as proteins, DNA, RNA, and lipids

This makes your skin more reactive and sensitive

Antioxidants, 11(5), Article 1026

PLoS One 7, e43249

Such findings, together with the growing awareness of the importance of Se to general health, require further work primarily on creating an acceptable range of blood Se concentration or other measures to determine optimal Se consumption and, consequently, to guarantee adequate Se supplementation in populations at high risk of low Se intake