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Taken together, these data demonstrate that cancer cells capable of enduring 5FU treatment have significant, sustained mitochondrial adaptations, driving enhanced mitochondrial biogenesis and fusion in the absence of evident mitochondrial dysfunction

Furthermore, we focused on the marked differences between normal and disease conditions during the growth process (Figures 3, 4) and suggested that the metabolite variety was affected by DPSC treatment during disease progression

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10.1089/ars.2017.7217 26 DikalovaA.AschnerJ

However, other models may demonstrate different appearance