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Description

Mitochondrial ubiquitin ligase alleviates Alzheimers disease pathology via blocking the toxic amyloid- oligomer generation

PloS Pathog (2021) 17:e1009746

Total appointment 45 min 1 hour

The c-MET/HGF complex structure reveals that, by utilizing two distinct interfaces, one HGF molecule is sufficient to induce a specific dimerization mode of c-MET for receptor activation

CB-839, a selective glutaminase inhibitor, has anti-tumor activity in renal cell carcinoma and synergizes with cabozantinib and everolimus, in keystone symposia, tumor metabolism: Mechanisms and targets