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In the process of metabolism of formaldehyde, the formaldehyde may first combined with glutathione (GSH) to form the product of S-hydroxymethyl glutathione (HM-GSH), then FALDH in cytoplasm will catalyzes the formation of a S-formyl glutathione (F-GSH)

Loss of AJs can cause decreased BBB integrity and increased permeability

Increased risk of inflammatory bowel disease in women with endometriosis: a nationwide Danish cohort study

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In the presence of such a causative agent, one of the TRP channels, namely TRPV1, may be triggered