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ACS Applied Materials & Interfaces, 2019, 11(34): 3055130565 Li X, Zhao C, Deng G, Liu W, Shao J, Zhou Z, Liu F, Yang H, Yang S

It exists as two enantiomers: (R)-(+)-lipoic acid (R-ALA) and (S)-()-lipoic acid (S-ALA), and as a racemic mixture

An in vitro experiment was also a part of this study

In addition, manganese oxide nanomaterials (MONs), including MnO 2 , Mn 2 O 3 , and Mn 3 O 4 , possess a similar GSH elimination property to Cu-based nanomaterials, and react with GSH along with the decomposition of MnO x into Mn 2+ for initiation of the Fenton-like reaction (Qian et al., 2020)

This pathway has been studied in several in vitro models and is under investigation as a potential therapeutic target in several cancers, including breast, ovarian, liver, and prostate 15,16,17,23