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10.1016/j.pharmthera.2021.107916 87 PettieJ

( Response: We are not considering in this rulemaking for CY 2025 whether to recategorize provisional codes as permanent because we intend to conduct a comprehensive analysis of all such provisional codes, which we expect to address in future rulemaking

See the details in the Concerns and Cautions section of our Quercetin and Rutin Supplements Review

16 Furthermore, NAPQI binds to complexes I and II, disrupting the electron transport chain and allowing electrons to escape and produce superoxide radicals