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Funding This work received support from the Consejo Nacional de Ciencia y Tecnologa (CONACYT) FOSEC SEP-INVESTIGACIN BSICA A1-S-26479, and the International Society for Neurochemistry-CATEGORY 1C: Return Home grant to AME-S

Acknowledgements This work was supported by the National Natural Science Foundation of China (81902422, 82403008), the China Postdoctoral Science Foundation (2024M762749), the Natural Science Foundation of Jiangsu Province (BK20231245, BK20250559), the program of Jiangsu Traditional Chinese Medicine Science and Technology Development (No.MS2024140), the key program of Jiangsu Provincial Health Commission (K2025009), Social Development Program of Yangzhou Science and Technology Bureau (No.YZ2025094), Yangzhou City Basic Research Program (Joint Special Project) - Health and Wellness Category (2024-2-08, 2025-2-08, and 2025-3-15), Natural Science Foundation of Minhang District (2025MHZ052)

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