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Neurology 43 , 817824 (1993)

For individuals concerned about preserving lean mass, especially during periods of caloric restriction, sermorelin is not a weight-loss medication

Interestingly, TSH and fT3 changes were completely reversible following significant weight loss (33% BMI decrease) [62]

The same investigators also found that selenium supplementation resulted in the upregulation of PPAR- and GLUT-1 , along with the downregulation of LDLR (86)