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It is an undesirable side effect of pharmacotherapy, characterized by symptoms such as changes in mental state, autonomic disturbances, or neuromuscular disorders

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10.3390/biom12070933 [DOI] [PMC free article] [PubMed] [Google Scholar] Acharya S., Suwas S., Chatterjee K

Additionally, bFLS expresses mostly MCT-1 and its pharmacological inhibition with AR-C155858 was shown to significantly reduce IL-6 and IL-8 secretion induced by D-lactate (90)

For instance, studies demonstrate distinct gene expression patterns and immune cell infiltrates between eutopic and ectopic tissues, and across lesion locations, suggesting variable responsiveness to immunomodulatory or microbiome-targeted therapies ( Future therapeutic frameworks should thus integrate phenotypic, molecular, and patient-specific factors to guide individualized treatment