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Metformin, the first-line treatment recommended by NICE for type 2 diabetes, interferes with vitamin B12 absorption in the gut through a calcium-dependent mechanism

and v) with the CDAA diet with rifaximin and L-carnitine, as previously described (23,24)

doi: 10.1016/j.hoc.2012.02.002 217

For the remainder of this section, we will focus on parvalbumin chandelier cells since these are the interneurons known to play a major role in prefrontal cortexdependent working memory and also have been implicated in the pathophysiology of neuropsychiatric disorders such as schizophrenia [60, 62]

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