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Anton R, Boskou SBD, Castle L, et al

Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation

There have been some reports of digestive discomfort when people take large doses of L-carnitine

Aug 2016;33(8):981-91

In selecting our winner overall and the winners for various subcategories included in our summary of recommendations, we gave the most weight to effectiveness, and safety was close behind