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The impact of changed redoxin function on ferroptosis could also be based on secondary effects, e.g., the increase in superoxide formation upon loss of mitochondrial redoxins [90,91] or activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway [92,93] , a major regulator of transcription of antioxidant and anti-ferroptotic enzymes [65]

Spacing from heavy meals supports better absorption

Neuroprotection: It helps protect brain tissue from oxidative stress, which is linked to neurodegenerative conditions

So I mentioned in the introduction, like this word, antioxidants, and you've mentioned vitamin C now, glutathione, for listeners, because I think people hear antioxidants and they think, oh, like good things that, you know, help us

Plasmid constructs and cell procedures Plasmid constructs expressing human WT SOD1 (SOD1 WT ) and human SOD1 with G93A mutation (SOD1 G93A ) originally generated by the Fisher lab were obtained through Addgene 20