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Epithalon structure and discovery Chemical composition: Tetrapeptide (four amino acids) Sequence: Ala-Glu-Asp-Gly (AEDG) Also called Epitalon or Epithalone Synthetic version of epithalamin (pineal gland extract) Molecular weight: 390.35 g/mol Water-soluble peptide Discovery history: Discovered by Professor Vladimir Khavinson in St

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3.4 Non-natural peptides with anti-melanin synthesis activities In an experiment conducted in Italy to develop nontoxic natural tyrosinase inhibitors, reversed-phase high-performance liquid chromatography (RP-HPLC) and ultraviolet detection were used to study the inhibitory effects of various dipeptides on DOPA pigment formation

282 Furthermore, specific amino acids such as glycine, proline, and lysine are particularly important for collagen synthesis