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10.1186/S12935-016-0355-9 126 WangL.HuangH.LiuD.FangS.XianY.ZhouJ.et al (2012)

Notably, after a 4-week washout period these beneficial effects diminished, with the exception of clinical severity scores

[14] Always feel free to discuss with your provider why NAD+ is recommended in your case and what the current evidence is, since it is a newer therapy outside of standard FDA-approved treatments