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Description

In vitro studies showed that PROTAC 61 (LWY713) exhibited nanomolar degradation potency (DC 50 = 0.64 nM, D max = 95%) in FLT3-ITD AML MV4-11 cells

But promising results in rats do not reliably predict what will happen in people

(2024) 84:427436.e1

Its so stunning

Assessing whether ferroptosis and its related molecules play essential roles in infertility, metabolic abnormalities, and other aspects of clinical PCOS and whether the administration of antioxidants can prevent ferroptosis, lipid peroxidation, and adverse maternal and fetal outcomes caused by maternal hyperandrogenemia and IR will provide insights and directions for future clinical diagnosis and treatment