Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model
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Malik RA, Tesfaye S, Ziegler D
The HDACis discussed in this review are targeting one or multiple classes, constituted of several HDAC proteins: epigenetic drugs targeting class I (HDAC1, 2, 3 and 8), class IIa (HDAC4, 5, 7 and 9) and/or class IIb (HDAC6 and 10) (Fig
