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Future studies are needed to reconcile the underlying differences between tumor tissue and basal PTC cell line GPX4 expression levels and in vitro responses to pharmacologic inhibition of GPX4 within an emulated 3D thyroid tumor microenvironment in vitro and in vivo

!Corticosteroids - Both affect cortisol/HPA axis

The ferroptosis marker PTGS2 was significantly reduced in MMPP-treated mice compared with that in control mice treated with LPS to induce sepsis

Lipids Astrocytes are well known for their ability to metabolize exogenous fatty acids via mitochondrial -oxidation and to subsequently utilize fatty acid-derived acetyl-CoA for oxidation to CO 2 in the mitochondrial citric acid cycle or for ketogenesis, both in culture [147, 181,182,183,184] and in brain slices [185, 186]

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