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In practice, activity pacing is guided by several key principles: (i) Understanding Energy Limits: Patients learn to recognize their personal energy thresholds, identify early signs of overexertion, and abstain from activities that exceed these limits [173]

W., Coppola, V., Tessarollo, L., Schomburg, L., Kohrle, J., Hatfield, D

This accounts for 4 weeks at each dose level: (2x4) + (4x4) + (8x4) + (12x4) = 8 + 16 + 32 + 48 = 104mg

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