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For analysing acyl sugars extraction, we used an LC-MS system, which is a Waters Acquity UPLC system coupled in tandem to a Waters photodiode array (PDA) detector and a SYNAPT G2-Si HDMS QTOF mass spectrometer (Waters, Manchester, UK)

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FIGURE 3 Glial cytoplasmic inclusion of S is the pathological hallmark of multiple system atrophy

doi: 10.1007/s00401-023-02595-9 99

For further in vivo studies we plan to apply both, helper-dependent Ads and immune shielding, to deliver both our strategies in one Ad and prevent immune recognition