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Principles are lovely things, but when it comes to improving the lives of animals, sometimes the opera must be interrupted

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Finally, to establish causality, we predict that disrupting this antioxidant mismatch in ex vivo assays will demonstrate superior efficacy in restoring T-cell function compared to standard immune checkpoint blockade (ICB) alone

Also, it emphasized interspecies differences and the fact that the response in pathophysiologic stages is significantly different from normal physiologic stages