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[58] The distinction between nicotine and tobacco smoke is central to discussions of smoking-related diseases

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Although pipe smoke can have greater nicotine levels than cigarettes it's more alkaline and makes it more likely to get into the bloodstream

They also confirmed their original findings that formaldehyde hemiacetals, a new form of formaldehyde, may serve as delivery agents that deposit more deeply in the lungs than gaseous formaldehyde