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The gut microbiota, a microbial community residing in the intestinal tract, plays a pivotal role in maintaining host health through homeostasis

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Cancer Res 82(19):34863498 Panda SK, Peng V, Sudan R, Ulezko Antonova A, Di Luccia B, Ohara TE et al (2023) Repression of the aryl-hydrocarbon receptor prevents oxidative stress and ferroptosis of intestinal intraepithelial lymphocytes

Washing State University has stated NRF2 to be: "The most extraordinary therapeutic and most extraordinary preventive breakthrough in the history of medicine." Additionally, they stated the following: "Nrf2 is argued to be both lifespan and healthspan extending." "Nrf2 is likely to be the most important health promoting approach into the foreseeable future." - Source

Cancer 91 , 17451751 (2001)