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While targeting GPX4 holds promise in cancer treatment, a challenge arises from its widespread expression in both cancer and immune cells, which can potentially cause side effects when using traditional GPX4 inhibitors

It is hard to reduce the total body load if one is continually exposed to the toxin

This would tentatively suggest that GSHee exerts positive effects in brain regions such as the Klliker-Fuse and pre-Btzinger complex, which generate/control rhythmic breathing 121,122,123,124,125,126,127,128,129,130,131,132 , although to our knowledge there is no reports as to the direct effects of GSH in these neuronal complexes

113 , E7564E7571 (2016)

The flow rate was 0.6 mL/min, and the injection volume was 3 L