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While the direct link between Sb9 and mast cell activation is yet to be comprehensively elucidated, it is conceivable that Sb9s modulation of GzmB activity could influence the release of mediators from mast cells, thereby impacting allergic reactions, asthma and inflammatory responses

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[DOI] [PubMed] [Google Scholar] 27.Rahman I, Kode A, Biswas SK

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271,272 Additionally, hyperglycemia-induced oxidative and nitrosative stress activates poly(ADP-ribose) polymerase (PARP), a nuclear enzyme involved in DNA repair

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