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Residues 670675 in the N-terminal portion of the unliganded -CT is dragged upward by the liganded -CT, and make close contact with the lower part of FnIII-1 (Fig

20 It is well known that acute stress increases norepinephrine signaling, but chronic stress and stress-induced depression are associated with damage to neurons that produce norepinephrine and changes in norepinephrine receptor function in key regions of the brain

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