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CYP19A1 regulates chemoresistance in colorectal cancer through modulation of estrogen biosynthesis and mitochondrial function

Wold LE, Muralikrishnan D, Albano CB, Norby FL, Ebadi M, Ren J

Amyloid-beta peptide neurotoxicity in human neuronal cells is associated with modulation of insulin-like growth factor transport, lysosomal machinery and extracellular matrix receptor interactions

On this basis it is not surprising that oxidative stress has been implicated in a growing list of human diseases with a leading place occupied by diabetes [5-7] for two reasons, the first being the epidemic proportions that this disease is assuming

C-terminal truncation modulates alpha-Synucleins cytotoxicity and aggregation by promoting the interactions with membrane and chaperone