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The inhibition of somatostatin by DSIP has been found by a separate study, thus leading to the speculation that this peptide might have larger and more universal functions regarding human physiology than just primary sleep promotion, for which the direct inhibitory effects of somatostatin are more than peculiar

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Collagen is an important protein in the skin that helps give the skin its firmness and elasticity

Additional information Peer review information Nature Chemical Biology thanks Dohoon Kim and the other, anonymous, reviewer(s) for their contribution to the peer review of this work