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BioMed Research International , 2015.PMID: 26236730 Comprehensive review of GHK-Cu's effects on skin remodeling including collagen synthesis, glycosaminoglycan production, and growth factor expression

The ER also communicates with mitochondria via signaling from the unfolded protein response (UPR), which is activated by ER stress and signals through the three ER-resident stress sensors IRE1, PERK, and ATF6 (Walter and Ron, 2011)