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Off-target effects: Non-specific accumulation of MNPs in unintended tissues can reduce therapeutic efficacy and lead to unintended side effects

of this final rule with comment period, we proposed that the median payer-specific negotiated charges as reported on the Medicare cost report would be used in a proposed market-based methodology to calculate IPPS MS-DRG relative weights beginning in FY 2029 to reflect the relative hospital resources used to provide inpatient services to patients

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Where efficacy studies have shown higher protection rates in cats vaccinated with adjuvanted vaccines versus non- adjuvanted vaccines, the former are preferable in cats at high risk of infection

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