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Similarly, neutrophils and macrophages become activated as part of the host defense system as well as the inflammatory response, which produces a large amount of RNS and ROS, followed by the entry of these ROS into the erythrocytes [406]

Symptoms of vitamin C deficiency, such as poor wound healing and lethargy, result from impairment of these enzymatic reactions and insufficient collagen, carnitine, and catecholamine synthesis Vitamin C affects several components of the human immune system