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Zhuo J, Zeng Q, Cai D, et al

Chemopreventive agents: selenium

doi: 10.1146/annurev-pharmtox-010818-021441 202 Di MarzoVStellaNZimmerA

Alzheimer disease-specific conformation of hyperphosphorylated paired helical filament-Tau is polyubiquitinated through Lys-48, Lys-11, and Lys-6 ubiquitin conjugation

The sulfidation of AgNPs to the highly insoluble and biologically inert mineral Ag2S, a common process in anoxic sediments, effectively deletes the dominant toxicity pathway for pristine AgNPs by shutting down the release of toxic Ag+ ions.92,93 Similarly, the progressive oxidation of an nZVI particles reactive Fe0 core to a more benign iron (oxy)hydroxide shell concurrently neutralises both its remedial efficacy and its capacity to generate ROS via Fenton chemistry