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doi: 10.1007/s00726-007-0011-8

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These imbalances are associated with reduced GSH levels, a lower overall antioxidant capacity and the activation of nuclear factor kappa B (NF-B), a transcriptional factor for inflammatory pathways (Naik et al., 2011)

This restoration of NAD+ helps preserve RGC function and structure in animal models of glaucoma, especially in the face of elevated IOP and metabolic stress (187, 191, 192)

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