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Description

It can promote longevity in Saccharomyces cerevisiae by suppressing the generation and accumulation of extrachromosomal ribosomal DNA (rDNA) circles, which are considered a cause of aging in yeast (48)

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DNMT3A facilitates colorectal cancer progression via regulating DAB2IP mediated MEK/ERK activation

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[PubMed: 8292469] 188

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