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[] MOF-mediated hyperacetylation of ATP5B disrupts oxidative phosphorylation, leading to cardiomyocyte energy deficiency, which drives mitochondrial crista loss, fibrosis, and ventricular enlargement, ultimately culminating in HF

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Gandhi PU, Gaggin HK, Sheftel AD et al (2014) Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function

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