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Additionally, IL-6 and IL-23 can drive Th 17 differentiation, with IL-17 recruiting neutrophils that infiltrate thyroid tissue, causing direct damage to follicular epithelial cells (Stadhouders et al., 2018)

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Earlier studies showed that in the cerebral I/R model, oxidative stress enhances transcription factors such as NF-B, which is distributed in the neurons, microglial cells, and astrocytes