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Glutathione homeostasis and functions: potential targets for medical interventions

Knas et al., 2016

Separate studies demonstrated anti-anxiety effects in rats at remarkably low doses (0.5 mg/kg), with effects appearing within 12 minutes and including increased exploration of open and lighted spaces, a standard measure of reduced anxiety in rodent models

Concurrently, PPIs, frequently prescribed to diabetic patients for gastroesophageal reflux disease management, impair protein-bound vitamin B12 release from dietary sources in the non-acidic gastric environment, with prolonged use ( 2 years) conferring a 65% increased risk of deficiency [159]

So, in normal cell metabolism, you are always generating a little bit of hydrogen peroxide instead of water in the electron transport chain