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When I came home from work, all I could do was eat, watch TV, and fall asleep on the couch

This suggests that TCA cycle anaplerosis via pyruvate carboxylase (PC) was stimulated by SAAR

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Once there exists an accumulation of DAMPs, it would trigger the amplification of tissue inflammation, leading to more severe inflammation and CD, forming a vicious circle and disrupting the normal physiological function of tissues and organs (Linkermann et al., 2014