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Physical exertion produces a hyperregulation of the nuclear factor kappa B and mitogen-activated protein kinase that activates gene expression of a number of enzymes and proteins with an important role in maintaining oxidative/antioxidant intracellular homeostasis (Antonioni et al., 2019)

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21,22 To some authors, arterial stiffness is a precursor to atherosclerosis, diastolic dysfunction, hypertension, and impaired cerebral/coronary blood flow, whereas others discuss arterial stiffness as a result of chronic risk factors such as hypertension and its own symptoms

Cancer Therapies 17 (1), 8091