pancreatic cancer glutathione enhancement Targeting glutamine dependency confers vulnerability to GPX4-dependent ferroptosis: Cell Reports Medicine Frontiers | Targeted drug delivery

In ROS-rich microenvironments, these moieties undergo bond cleavage or oxidation-driven hydrophilization, which in turn triggers drug release

Given that mitochondrial one-carbon metabolism is very important for cancer progression, the entry of serine into the mitochondria is a critical step in the generation of one-carbon units

Int J Qual Methods

These assays are implemented on microfluidic paper-based devices, and the mechanism involves reduction of gold salt Au 3+ to Au 0 by glucoses aldehyde group and nucleation of Au seeds, leading to red color shifts proportional to glucose concentration

Das bedeutet: Es findet eine moderate bis aktive Redoxreaktion statt der Krper verarbeitet oxidativen Stress, aber (noch) ohne pathologische berlastung