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By establishing a temporal framework for liver organoid development, this work facilitates the standardized application of iHLOs across drug screening, toxicology testing, and disease modeling

doi: 10.1038/ismej.2008.108

Similarly, Rao et al (50) found that increased intracellular iron disrupts the neuromelanin-iron complex in neurons, releasing free iron ions that damage neurons and lead to neuromelanin leakage