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Subsequently compounds have recently been produced that interact with PRMT5 when bound to MTA, and which selectively target MTAP -negative cancer cells to varying degrees or elicit a synergistic effect in a MTAP -negative background (88, 89)

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En ese caso, las clulas T responsables de esas regulaciones comienzan a dividirse rpidamente y se vuelven proinflamatorias, lo que provoca una escasez de clulas T Th1 y Th17 [4]