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In cancer cells, erastin, a particular iron apoptosis-inducing chemical, increases heat shock factor 1 (HSF1)-dependent HSPB1 expression

Curcumin can induce apoptosis in pancreatic cancer cells line, both in vitro and in vivo [126]

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11 Conversely, in a study assessing a cream containing 0.1% GSH-C4, 0.5% beta-glycyrrhetic acid, and 10% azelaic acid, 10 percent of the participants discontinued due to lower skin irritation