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Several types of cancers, including glioblastoma, exhibit a high dependency on glutamine, also called glutamine addiction, and inhibition of these pathways has been shown to reduce tumor growth and induce cancer cell death 115,116,117,118

doi: 10.1074/jbc.M007339200 249 LaityJHAndrewsGK

27,28 Methadone maintenance is used to relieve narcotic craving, suppress the abstinence syndrome, and block the euphoric effects associated with opioids

The GST (glutathione-S-transferase) pull-down assay is a widely used biochemical technique that enables the investigation of protein-protein interactions in vitro