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Joanisse S, McKendry J, Lim C, Nunes EA, Stokes T, McLeod JC, et al

However, overexpression of Pfkfb3 activates glycolysis in neurons through the APC/C-Cdh1 pathway, which inhibits the pentose phosphate pathway (PPP), reduces the oxidation of glucose-6-phosphate (G6P), decreases the production of reduced glutathione, and finally leads to oxidative stress and apoptosis (Herrero-Mendez et al., 2009)

After being washed with 10 column volumes of PBS, the bound proteins were eluted using 10 mm glutathione (Solarbio, G8180) in PBS

Once daily administration of Depakote ER in pediatric patients (10-17 years) produced plasma VPA concentration-time profiles similar to those that have been observed in adults

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