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The disease specificity of these fungal microbiota changes indicates their potential utility as diagnostic biomarkers and therapeutic targets

Other studies show that calcium oxide crystals induce mitochondrial dysfunction in macrophages.[ref][ref] High dietary oxalate intake causes some, but not all, people to have statistically significant decreases in mitochondrial metabolic function.[ref] Animal models of high oxalate levels show that there is an increase in mitochondrial reactive oxygen species (ROS) that can lead to oxidative stress if glutathione is inadequate

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Apart from the cosmetic angle, many also report improved energy levels, reduced inflammation, and better immune function over time