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These endocrine abnormalities if not treated, culminate to metabolic syndrome development, in which the key pathophysiological components include abdominal fat accumulation, reduced systemic insulin sensitivity, low-grade inflammation, high blood pressure, high blood sugar levels, high triglyceride levels, and low levels of high-density lipoprotein (HDL) cholesterol [2]

Arenas J, Ricoy JR, Encinas AR, Pola P, DIddio S, Zeviani M, Didonato S, Corsi M

An analysis of the relative risk for goiter in euthyroid patients with type 2 diabetes

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But for those with certain liver enzyme differences or microbiomes that favor TMA production, the risk is tangible and manageable