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Description

Table 2 summarizes the pathogenicity of LMNA variants, providing an overview of associated phenotypes, swimming speed, muscle endurance, and heartbeat data for the LMNA mutations transgenic fish

The resulting supernatant was analyzed using high-performance liquid chromatography (HPLC, VWR Hitachi, Radnor, Pennsylvania, USA) coupled with mass spectrometry (3200 Q Trap, AB Sciex, Framingham, Massachusetts, USA) to quantify the target compounds